HIFU procedure : is it painful ?

The procedure is not painful because it is done under general anaesthesia to avoid any movement of the patient. The post-procedure effects are not painful, but patients may feel a slight discomfort that dissipates after a few hours. As the procedure is non-invasive, there is no scarring and no burning sensation usually associated with radiotherapy.[1]

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[1] A Abreu, et al. (2020). High Intensity Focused Ultrasound Hemigland Ablation for Prostate Cancer: Initial Outcomes of a United States Series. Journal of Urology, 204(4), 741-747. https://doi.org/10.1097/JU.0000000000001126