The procedure is not painful because it is done under general anaesthesia to avoid any movement of the patient. The post-procedure effects are not painful, but patients may feel a slight discomfort that dissipates after a few hours. As the procedure is non-invasive, there is no scarring and no burning sensation usually associated with radiotherapy.
 A Abreu, et al. (2020). High Intensity Focused Ultrasound Hemigland Ablation for Prostate Cancer: Initial Outcomes of a United States Series. Journal of Urology, 204(4), 741-747. https://doi.org/10.1097/JU.0000000000001126